胰高血糖素(Glucagon)说明
目录编号:HOR-286
中文名称:胰高血糖素(Glucagon)
英文名称:Glucagon
胰高血糖素(Glucagon)序列号: H-His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-OH.
胰高血糖素(Glucagon)(FSH)简介: Glucagon Human Synthetic peptide is a single, non-glycosylated, polypeptide chain containing 29 amino acids and having a molecular mass of 3485 Dalton. The Glucagon is purified by proprietary chromatographic techniques.
胰高血糖素(Glucagon)背景: Glucagon is an important hormone involved in carbohydrate metabolism. The hormone is synthesized and secreted from alpha cells (?-cells) of the islets of Langerhans, which are located in the endocrine portion of the pancreas. Glucagon is released when the glucose level in the blood is low (hypoglycemia), causing the liver to convert stored glycogen into glucose and release it into the bloodstream. The action of glucagon is thus opposite to that of insulin, which instructs the body’s cells to take in glucose from the blood in times of satiation.
Glucagon is beneficial for the culture of some cell types. It has been used in some biochemical regulation studies of glycogenolysis in hepatocytes. It has been also been found to induce DNA replication in primary cultures of adult rat hepatocytes when used in combinations with EGF and Insulin. Glucagon increases the blood glucose concentration by promoting rapid breakdown of liver glycogen, and also acts to relax smooth muscle such as the gastrointestinal tract.
来源宿主:
产品规格:
溶解建议:
提供的胰高血糖素产品为白色无菌冻干粉末,冻干粉里不含有其它添加剂.推荐使用无菌的18MΩ的超纯水来溶解,浓度不低于100ug/ml,便于后续稀释.
稳定性说明:
Glucagon although stable at room temperature for 3 weeks, should be stored desiccated below -18℃. Upon reconstitution Glucagon should be stored at 4℃ between 2-7 days and for future use below -18℃. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
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