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人胰高血糖素样肽1(GLP1)
人胰高血糖素样肽1(GLP1)

人胰高血糖素样肽1(GLP1)

胰高血糖素

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产品介绍

人胰高血糖素样肽1(GLP1)说明

 

目录编号HOR-284

中文名称:人胰高血糖素样肽1(GLP1)

英文名称:Human Glucagon Like Peptide-1

人胰高血糖素样肽1(GLP1)序列号:  The sequence of the first five N-terminal amino acids was determined and was found to be His-Ala-Glu-Gly-Thr..

人胰高血糖素样肽1(GLP1)(FSH)简介:   Glucagon Like Peptide-1 is a single, non-glycosylated, polypeptide chain containing 30 amino acids and having a molecular mass of 3298.7 Dalton. The GLP-1 is purified by proprietary chromatographic techniques.

人胰高血糖素样肽1(GLP1)背景:   Glucagon-like peptide-1 (GLP-1) is derived from the transcription product of the proglucagon gene. The major source of GLP-1 in the body is the intestinal L cell that secretes GLP-1 as a guthormone. The biologically active forms of GLP-1 are: GLP-1-(7-37) and GLP-1-(7-36)NH2.

GLP-1 secretion by L cells is dependent on the presence of nutrients in the lumen of the small intestine. The secretagogues (agents that causes or stimulates secretion) of this hormone include major nutrients like carbohydrate, proteinand lipid. Once in the circulation, GLP-1 has a half life of less than 2 minutes, due to rapid degradation by the enzyme dipeptidyl peptidase-4.

GLP-1 possesses several physiological properties that make it a subject of intensive investigation as a potential treatment of diabetes mellitus. The known physiological functions of GLP-1 include: Increases insulin secretion from the pancreas in a glucose-dependent manner, decreases glucagon secretion from the pancreas, increases beta cells mass and insulin gene expression, inhibits acid secretion and gastric emptying in the stomach, decreases food intake by increasing satiety.

来源宿主:

产品规格:

1mg

5mg

100mg

溶解建议:

提供的人胰高血糖素样肽1(7-36)产品为白色无菌冻干粉末,冻干粉里不含有其它添加剂.推荐使用无菌的18MΩ的超纯水来溶解,浓度不低于100ug/ml,便于后续稀释.

稳定性说明:

Lyophilized Glucagon Like Peptide-1 although stable at room temperature for 3 weeks, should be stored desiccated below -18℃. Upon reconstitution GLP-1 should be stored at 4℃ between 2-7 days and for future use below -18℃. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

人胰高血糖素样肽1(GLP1)具体请咨询在线客服,或者来电索要详细说明书!

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