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人内皮素1(EDN1)
人内皮素1(EDN1)

人内皮素1(EDN1)

内皮素

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021-60348496

产品介绍

人内皮素1(EDN1)说明

 

目录编号HOR-307

中文名称:人内皮素1(EDN1)

英文名称:Human Endothelin-1

人内皮素1(EDN1)序列号:   

Cys-Ser-Cys-Ser-Ser-Leu-Met-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-As p-Ile-Ile-Trp.

人内皮素1(EDN1)简介:

EDN1 contains 21 amino acids having a molecular mass of 2491.95 Dalton.

人内皮素1(EDN1)背景:

EDN1 is a powerful mitogen mediator of smooth muscle tone, and inflammatory regulator that is involved in diseases of the airways, pulmonary circulation, and inflammatory lung diseases, both acute and chronic. Endothelin-2 and Endothelin-3 vary from Endothelin-1 by two and six amino acids, respectively, and share homology, particularly at the carboxy terminus with sarafotoxins a-e. The lung has the largest levels of EDN1 secreted by endothelium, smooth muscle, airway epithelium, and a diversity of other cells. ET-1 also circulates in the plasma. Endothelin-1 along with endothelin-2, & endothelin-3 (ET-3) consist of the endothelin family of 21 amino acid peptides manufactured in a variety of cells and tissues, particularly endothelial and epithelial lineages. These endothelins are derivatives from three genes. The endothelins are normally connected with hypertension, though they regulate a diversity of other effects through two G-protein coupled receptors, ET-A and ET-B. The endothelins are derivatives from a precursor peptides using cleavage by metalloproteases for instance endothelin-converting enzymes.

来源宿主:

产品规格:

5mg

25mg

100mg

溶解建议:

提供的人内皮素1产品为白色无菌冻干粉末,冻干粉里不含有其它添加剂.推荐使用无菌的18MΩ的超纯水来溶解,浓度不低于100ug/ml,便于后续稀释.

稳定性说明:

Lyophilized EDN1 although stable at room temperature for 3 weeks, should be stored desiccated below -18℃. Upon reconstitution EDN1 should be stored at 4℃ between 2-7 days and for future use below -18℃. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

人内皮素1(EDN1)具体请咨询在线客服,或者来电索要详细说明书!

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